If we're going to decide this through a taste test, I would say no.
Organic and pure vanilla are the same, an alcohol base for the vanilla bean that produces the tell-tale vanilla flavor.
I have tried both imitation vanilla and real vanilla in my recipes; those do make a difference. The lighter and more delicate the food, the more inclined I am to use real pure vanilla.
For those recipes where there are a lot of ingredients and vanilla happens to be an accent, then I haven't tasted much difference. In terms of organic, I don't think the higher price delivers a better product.
What do you think?